News & Views

Adherence (Part 2) – Is adherence to phosphate binder therapy associated with improved outcomes?

Research and clinical experience suggests that adherence to phosphate binders is low, but will improving adherence lead to better outcomes? A meta-analysis of 21 studies, in diseases such as HIV, myocardial infarction and type II diabetes, found that “good adherence to drug therapy is associated with positive health outcomes.”[1]  But…

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Date of publication:
April 11, 2014

News & Views

Adherence (Part 1) – The challenge of non-adherence in hyperphosphatemia

Phosphate binders have been shown to be effective in regulating phosphorus levels [1,2] and yet according to a recent large observational study, 50% of patients have serum phosphorous concentrations outside the target range. Clinical studies have demonstrated the efficacy of phosphate binders in controlling serum phosphorus and observational studies confirm…

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Date of publication:
March 24, 2014

News & Views

What are the causes of patient non-adherence to hyperphosphatemia treatment? (Part II)

Previously in our series on non-adherence, we assessed how improved patient education could positively impact the 50%+ non-compliance rate in hyperphosphatemia treatment. In this article we assess the following questions: How does a patient’s drug preference impact their adherence to treatment? Why do patients prefer some treatments over others? How does…

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Date of publication:
May 29, 2012

News & Views

What are the causes of patient non-adherence to hyperphosphatemia treatment? (Part I)

Non-adherence to treatment regimens in hyperphosphatemia is a significant treatment challenge, with over 50% of patients non-compliant by some measures. In this series of articles we examine the factors that contribute to this low adherence, including: patient demographics; patient education and guidance; psychosocial factors, such as a patient’s perception of…

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Date of publication:
May 16, 2012

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