News & Views

Meeting the challenges of individual variation in phosphate control

Hyperphosphatemia remains a problem for many patients on hemodialysis, despite advances in understanding and pharmaceuticals. This is primarily thought to be a result of non-compliance to medication and/or diet by the patient. However, a recent perspective article in the American Journal of Kidney Disease raises the possibility of factors contributing…

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Date of publication:
March 11, 2016

News & Views

Updates in the battle against non-adherence to phosphate binders

The association between hyperphosphatemia and increased mortality and hospitalization in patients with end-stage renal disease (ESRD) on hemodialysis (HD) is well known, yet non-adherence to phosphate-binding treatment and dietary restrictions remains a significant problem.[1] Three recent papers have examined the range of factors influencing adherence, while a fourth discusses the…

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Date of publication:
February 17, 2016

News & Views

The Economic Impact of Improving Phosphate Binder Therapy Adherence

Low adherence to phosphate binders is recognized as a key contributor to poor control of hyperphosphatemia in dialysis patients.[1] Whilst various methods to improve adherence to phosphate binders have been studied, the impact on healthcare cost of poor binder adherence has only recently been analysed. Ramakrishnan et al created a…

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Date of publication:
November 18, 2015

News & Views

ERA-EDTA (Part 5) – understanding non-adherence to phosphate binders

In our continuing video series from the ERA-EDTA 2014 Congress, Professor Corinne Bagnis discusses results from the CHEOBS study, which aimed to provide a better understanding of non-intentional non-compliance with phosphate binder regimens. The study analysed the responses of approximately 300 haemodialysis patients to a 50-item adherence questionnaire, organized at…

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Date of publication:
August 22, 2014

News & Views

ERA-EDTA (Part 3) – A new perspective on improving compliance with phosphate binder therapy

In our continuing video series from the ERA-EDTA 2014 Congress, Viatcheslav Rakov from Vifor Pharma explains how an ethnographic study of dialysis patients identified three different patient groups, based on their ability and willingness to manage their own condition: Afflicted patients, who typically consider themselves depressed, are limited in their…

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Date of publication:
July 29, 2014

News & Views

Adherence (Part 8) – COMPACT expert view: Dr Stuart Sprague on the importance of low pill burden in the treatment of hyperphosphatemia

In a new video interview for COMPACT, Dr Stuart Sprague from the University of Chicago discusses the optimal approach to phosphate management in dialysis patients. Dr Sprague highlights that effective, tolerable, and low pill burden phosphate binders are key to patient adherence in this highly medicated patient population.

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Professor Stuart M. Sprague
Expert article by:
Professor Stuart M. Sprague

Date of publication:
July 1, 2014

News & Views

Adherence (Part 6) – Improving adherence through treatment optimization and simplifying regimens

Patients can find it challenging to adhere to complicated treatment regimens. For example, elderly patients who have cognitive or memory impairments may find therapy compliance difficult,[1] and younger patients may struggle to adapt their lifestyle to treatment demands.[2] This article will look at different ways in which treatment strategies can…

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Date of publication:
May 22, 2014

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