Medical Education

Module 3: Anaemia therapy in patients with CKD

Iron deficiency anaemia (IDA) is an acknowledged co-morbidity of chronic kidney disease (CKD),(1,2) and the 2012 Kidney Disease: Improving Global Outcomes (KDIGO) clinical guidelines provide recommendations on its diagnosis and treatment as part of the management of anaemia in patients with CKD.(3) Iron therapy has become one of the mainstay…

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Date of publication:
June 5, 2017

Medical Education

Pathophysiology of Hyperphosphatemia

Loss of renal function can lead to reduced phosphate excretion, phosphate dysregulation and, over time, vascular calcification. This downloadable presentation summarizes the pathophysiology of phosphate dysregulation in CKD and examines the mechanisms by which vascular calcification may occur.

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Date of publication:
May 19, 2016

Medical Education

Hyperkalemia Disease State

Hyperkalemia is a common co-morbidity in patients with chronic kidney disease (CKD), heart failure, diabetes or those on concomitant medication, especially renin-angiotensin aldosterone system inhibitors used to treat hypertension.[1] The frequency of hyperkalemia increases linearly with the stage of CKD, while increasing severity of hyperkalemia is associated with higher mortality.[2]…

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Date of publication:
May 19, 2016

Medical Education

Module 2: The Pathophysiology of Iron Deficiency

Iron deficiency/iron deficiency-anaemia (ID/IDA) is a common co-morbidity of chronic kidney disease (CKD)[1,2] and, if left untreated, can worsen the outcome of patients who already have compromised renal function.[3] We also now know that ID is not a single condition, but comprise multiple ID syndromes, with or without anaemia, which…

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Date of publication:
October 9, 2015

Medical Education

Module 1: Physiology of iron metabolism

Iron deficiency (ID) is one of the most common nutritional deficiencies in the world and a major cause of anaemia.((1) In addition, ID alone or with anaemia – a condition known as iron deficiency anaemia (IDA) – is prevalent in patients with chronic kidney disease (CKD).(2,3) Despite its frequency, ID/IDA…

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Date of publication:
October 1, 2014

Medical Education

Putting Science into Practice: How to Manage Iron Deficiency/Anaemia Following Kidney Transplant in CKD

Case 2: 36-year old female renal transplant recipient Post-transplant anaemia is associated with higher rejection rates and worse graft survival, compared with non-anaemic renal transplant recipients.(1) Therefore, identifying all causes of anaemia, including iron deficiency, is essential to improve the long-term success of transplantation. However, determining the underlying cause of…

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Date of publication:
October 31, 2013

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