Date of publication: August 22, 2014

News & Views

ERA-EDTA (Part 5) – understanding non-adherence to phosphate binders

In our continuing video series from the ERA-EDTA 2014 Congress, Professor Corinne Bagnis discusses results from the CHEOBS study, which aimed to provide a better understanding of non-intentional non-compliance with phosphate binder regimens. The study analysed the responses of approximately 300 haemodialysis patients to a 50-item adherence questionnaire, organized at nine centres in France.



Good morning. I’m Professor Corinne Isnard Bagnis. I work in Paris in a university hospital, and the study I want to tell you a little bit about today is a study that we have done with two other colleagues in France. We interviewed almost 400 patients by asking them to answer a questionnaire. All those patients were dialysis patients, and we asked them to think about their phosphate chelator drug and to answer our questions.

So the main result that we observed here, is very interesting because, whatever the drug [the patients] take, they all complain about burden, and they all complain about the fact they have to take it so many times a day. They mostly like pills, which is kind of surprising because most companies today have launched other forms of the drugs that they don’t taste of much.

What’s interesting to see, as well, is depending on their age, they have a different view on the role of the treatment in their health. The youngest people feel that their health does not necessarily rely on the treatment. They feel maybe more self-confident, or they feel that a drug is not everything in their disease and in their life, whereas the eldest patients in dialysis really feel that they rely totally on the drug they take in order to improve their health.

So in a few words, what I would like to say is that this only gives you a few pieces of information that we can add to other studies to give the advice of maybe trying to customize as well as we can, the educational programs that we often provide our patients with. [We can] customize to their age, to their lifestyle, and to what they really need to receive from us in terms of information or counselling to help them out with their chronic disease in daily life.

Related abstract

Medication adherence to phosphate binders: the CHEOBS study. Abstract MP139, ERA-EDTA Congress 2014. Corinne Isnard Bagnis, Abdallah Guerraoui, Franck Zenasni, Laetitia Idier, Philippe Chauveau

See also the previous ERA-EDTA articles:

May 28th, 2014; ERA-EDTA (Part 1) – Preview of ERA-EDTA 2014

July 23th, 2014; ERA-EDTA (Part 2) – How every hospital could assess the phosphate content of local beverages using a standard assay

July 29th, 2014; ERA-EDTA (Part 3) – A new perspective on improving compliance with phosphate binder therapy

August 13th, 2014; ERA-EDTA (Part 4) – Identifying patients in need of more specific management of CKD-MBD

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