Case 1: 36-year old female with systemic lupus erythematosus (SLE)
Anaemia is a frequent occurrence in systemic lupus erythematosus (SLE), affecting most patients at some point during the course of their disease. A frequent cause of anaemia in SLE is suppressed erythropoiesis from chronic inflammation (anaemia of chronic disease or anaemia of chronic inflammation).(1)
This interactive case study was developed with the expertise and support of Professor Simon Roger (Director of Renal Medicine and Professor of Clinical Medicine, University of Newcastle, Australia), and describes a patient with SLE and concomitant CKD due to glomerulonephritis.
In this case, a 36-year old woman with SLE presents with symptoms of fatigue and inflammation. Review the results of her pathology work-up, determine the underlying cause of her symptoms, consider her treatment options and compare your decisions with those of Professor Roger. Key learning points throughout the case study will offer explanations regarding the correct strategy.
- Keeling DM, Isenberg DA. Haematological manifestations of systemic lupus erythematosus. Blood Rev 1993;7:199–207.