Medical Education

Advances in the Management of Hyperphosphatemia

In this presentation, recorded at a satellite symposium at the ERA-EDTA 2016 Congress, Professor Philip Kalra discusses clinical advances in the management of hyperphosphatemia. Topics covered include: The prevalence of vascular calcification in both non-dialysis and dialysis-dependent CKD, and the link between vascular calcification and increased mortality The associations between…

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Date of publication:
September 20, 2016

News & Views

Observational Studies of Iron Deficiency in Haemodialysis Patients

Observational studies are a significant source of clinically relevant information. A recent expert interview with Professor Kamyar Kalantar-Zadeh highlights the value of observational studies in assessing intervention use and outcomes in a real-world setting. This article provides an overview of some key studies examining iron deficiency and IV iron use…

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Date of publication:
September 9, 2016

News & Views

KDIGO Speaker’s Guide: Iron Management in Chronic Kidney Disease

In 2014 KDIGO held a Controversies Conference on the management of iron in patients with chronic kidney disease (CKD). Bringing together an international panel of experts, the conference was convened to discuss potential safety concerns surrounding the increasing use of intravenous iron in patients with CKD. Following on from the…

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Date of publication:
September 2, 2016

Expert Perspectives

Expert Round Table: How Can We Design Randomised Controlled Trials to Evaluate IV Iron Therapies?

Professor Iain C Macdougall is Professor of Clinical Nephrology at King’s College London and is renowned for his expertise in anaemia associated with chronic kidney disease. In this expert video, recorded for COMPACT RENAL, Professor Macdougall discusses: The strengths and limitations of past RCTs of IV iron Good clinical endpoints…

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Date of publication:
August 30, 2016

Expert Perspectives

Expert Round Table: The Value of Observational Studies in Assessing the Benefit/Risk of IV Iron Therapies

Professor Kamyar Kalantar-Zadeh has conducted numerous clinical studies on outcomes and epidemiology in kidney disease patients. In this video, recorded exclusively for COMPACT RENAL, Professor Kalantar-Zadeh provides his expert opinion on the value of observational studies related to iron therapies in CKD. He also highlights good examples of both observational…

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Date of publication:
August 4, 2016

News & Views

ERA-EDTA 2016: Latest Insights on the Safety of IV Iron Therapy

The 53rd ERA-EDTA Congress was held in Vienna this year, with an extensive program covering a range of topics relevant to its international nephrology audience. This summary provides highlights of the sessions on iron deficiency anemia in CKD patients. FIND-CKD study: The latest safety data Dr Simon Roger presented 1-year…

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Date of publication:
July 6, 2016

News & Views

ERA-EDTA 2016: The Burden of Hyperkalemia

The 2016 ERA-EDTA Congress featured two satellite symposia that highlighted the disease burden of hyperkalemia, as well as an oral session on mineral metabolism that discussed new potassium binder therapies (that are not approved at the time of writing in Europe). Two satellite symposia included presentations on the challenges associated…

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Date of publication:
June 23, 2016

News & Views

ERA-EDTA 2016: CKD-MBD Management and Associated Outcomes

The ERA-EDTA 2016 congress was held last month in Vienna, Austria. Here is COMPACT RENAL’s round-up of the highlights in CKD-MBD. Non-calcium phosphate binders and reduced mortality Non-calcium phosphate binders reduce calcium loading in dialysis patients and may reduce risk of death compared with calcium-based phosphate binders, but it is…

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Date of publication:
June 17, 2016

News & Views

Proactive IV Iron Therapy in Haemodialysis Patients: The PIVOTAL Trial

As highlighted by the recently published KDIGO Controversies Conference findings, questions remain regarding the benefits and safety of IV iron use in patients with chronic kidney disease (CKD). An ongoing study which hopes to provide many of the answers is the “groundbreaking” PIVOTAL Trial.[1] Led by Dr Iain Macdougall, Professor…

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Date of publication:
May 19, 2016

News & Views

Highlights from the FIND-CKD Study

The FIND-CKD study results reported by Iain Macdougall and colleagues provide much needed information on the effects of IV iron therapy in non-dialysis-dependent chronic kidney disease patients.[1] 626 patients from 20 countries met the inclusion criteria, which included: CKD Stage 3-5ND Relatively stable eGFR decline No exposure to ESA therapy…

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Date of publication:
May 19, 2016

News & Views

Practice Guidelines for Iron Deficiency and Anemia in CKD

Iron deficiency anemia is common in patients with chronic kidney disease (CKD). As kidney function declines, the incidence and prevalence of anemia increases, particularly in patients with more advanced CKD. Anemia occurs due to loss of functional kidney mass and can be worsened by gastrointestinal bleeding, hemodialysis, frequent blood sampling,…

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Date of publication:
May 19, 2016

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